TMEM166 anticorps

N° du produit ABIN6719564

L’anticorps Lapin Polyclonal anti-TMEM166 a été validé pour WB, IHC, IHC (fro), FACS et ICC. Il convient pour détecter TMEM166 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TMEM166 anticorps (ABIN6719564)

Antigène: TMEM166 (FAM176A) (Family with Sequence Similarity 176, Member A (FAM176A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM166 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-TMEM166 anticorps

Fonction: Anti-TMEM166/EVA1A Antibody Picoband®

Séquence: MRLPLSHSPE HVEMALLSNI LAAYSFVSEN PERA

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TM/EVA1A Antibody Picoband® (ABIN6719564). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human TMEM166/EVA1A, which shares 66.7% and 50% amino acid (aa) sequence identity with mouse and rat TMEM166/EVA1A, respectively.

Isotype: IgG

Information d'application

Indications d'application: 1. Sun W, Ma XM, Bai JP, Zhang GQ, Zhu YJ, Ma HM, Guo H, Chen YY, Ding JB (2012). "Transmembrane protein 166 expression in esophageal squamous cell carcinoma in Xinjiang, China". Asian Pacific Journal of Cancer Prevention. 13 (8): 3713-6. 2. Wang L, Yu C, Lu Y, He P, Guo J, Zhang C, Song Q, Ma D, Shi T, Chen Y (August 2007). "TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis". Apoptosis. 12 (8): 1489-502.

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur TMEM166

Antigène: TMEM166 (FAM176A) (Family with Sequence Similarity 176, Member A (FAM176A))

Autre désignation: EVA1A

Sujet:

Synonyms: Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166, EVA1A, FAM176A, TMEM166, SP24

Tissue Specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Background: Eva-1 homolog A (C. elegans) is a protein that in humans is encoded by the EVA1A gene. It belongs to the FAM176 family. This gene is mapped to 2p12. EVA1A, also called TMEM166, acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.

Poids moléculaire: 21 kDa

ID gène: 84141

UniProt: Q9H8M9